IgG antibodies are commonly used in the treatment of cancer. It helps the body’s immune system fight cancer and is considered an alternative to chemotherapy and radiotherapy. A scientific team is doing research on a new type of antibodies that activate the body’s immune system and target cancer cells. Breast and ovarian cancer can slow down the growth of tumors.
Good news for cancer patients
An antibodies called IGG are usually used as immunotherapy to treat cancer. It helps the body’s immune system fight cancer and is considered an alternative to chemotherapy and radiotherapy. However, this treatment is not effective in some patients, especially in Her2-related breast and ovarian cancer, and sometimes resistance to this treatment develops in the body.
London scientists researched
To deal with this problem, scientists at King’s College London researched a separate type of antibody called IGE. This antibody activates the immune system in a different way than IGG. IGE antibodies activate immune cells in the body that are not generally active and are present around the tumor. This causes cancer cells to become directly targeted.
This was revealed in research.
Researchers prepared and tested IGE antibodies in place of IGG Antibody. Researcher Dr. Heather Bax, King’s College London, said IGE activated the immune system against Her2 -affected cancer cells and slowed down the development of tumors in mice. This tumor was developed in mice that had no effect on traditional remedies. This shows that this new technology can be beneficial for patients on whom current treatment is not working.
This will benefit cancer patients.
In further studies, scientists found that IGE antibody could re -activate the immune system around the tumor. This increases the immune system to fight cancer. The research is published in the Journal for Immunotherapy of Cancer (JITC). According to Dr. Heather Bax, “About 20% of the breast and ovarian cancer contain a marker called Her2. We have developed an IGE antibody against Her2 and found that it can activate the immune system in a new way. It can effectively target Her2 cancer cells. Especially in cases where current treatment is not working.” He further stated that this new discovery can become a new treatment option for patients suffering from her2 cancer.
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